Ravi Kane was born on 15 June 1972 in Neperveel USA. He recrived B.S.Chemical Engineering with distinction from Stanford University in 1993. While at Stanford University he received the Terman award for outstanding achivement in engineering, the American Institute of chemists outstanding seminar award, was a winner of AlChE Western regional Students paper contest and was elected to Tau BEta Pi, and Phi Beta Kappa honor societies. He received MS in Chemical Engineering Practice and Ph.D. in Chemical Engineering from graduate school of MIT. While at MIT he was an NSF graduate fellow, was elected to the Sigma xi honour society and won an from the epartment of Chemical Engineering. 

Career Highlights - 

After post-doctorate in chemistry and chemical biology at Harvard University, he joined Rensselaer Polytechnic Institute as Assistant professor in 2001, was promoted to associate professor in 2008. While at RPI Prof. Kane has named by MIT’s Technology Review, as one of the TR100- the top 100 young innoventors in the world – in 2004. In 2008 he received NYSTAR Faculty Development Award, an A1ChE nanovator Award, nad was selected as the Dr. G.P. Kane Visiting Professor in Chemical Technology, Mumbai in 2009. Prof Kane Development Award, an A1ChE nanovator Award, nad was selected as the Dr. G.P. Kane Visiting Professor in Chemical Technology, Mumbai in 2009. Prof Kane has graduated 12 Ph. D. students at RPI, has advised numerous undergraduates in the laboratory, and has contributed to over 75 scientific publications.

In 2009  Prof. Kane received  the trustees Outstanding Teacher Award at RPI. Prof. Kane is also a member of the editorial board for the Annual Review of Chemical and Biomolecular Engineering and Biotechnolgy and Biaengineering.

Research Areas – 

Kane’s group is investing and solving problems in biology and medicine through molecular engineering of nano material and interfaces. His research is focused in four areas : design of multivalent inhibitors and effectors, gene therapy , design of nanostructure biosensors, and cellular microenvironment engineering.

Kane’s team is designing multivalent nanoscale therapeutics for a number of deseases including AID’s antrax and influenza. Members also are designing multivalents molecules that can activate biological systems and elicate cellular response by clustering cellular receptors. 

In this gene therapy, Kan;s group is developing novel strategies to overcome major obstacles that are hiding advancement of this form of treatment. One of the better-developed approaches to gene delivery employs the natural ability of viruses to deliver their DNA to human cells. However the broad tropisms and these viral vectors and antibody-medicated clearance of the vectors are a major barrier in preventing clinical gene therapy.

His team is also devising strategies for functionlizing nanostructured materials with polymers and with biomolicules, such as enzymes and DNA. This technology may be useful for the designing of high density miciarrays. Researchers also are working on other approaches for designing sencers for toxins and pathogens.

In the area of cellular behavior, kane’s team is using the tools of microfabrication and genomics to investigate the molecular basis of cellular response to microenvironments. They are also using these microfabrication tools to influence the differentiation of stem cells. Selected Publication:

Bifunctional Polymers Presiting vancomycin and Flurescein theat direct. Anti-Flurescein Antibodies to self-Assembled Monolayers Prsinting D-Alanine-D-Alanine-Journal of American Chemical Society.

Kosmotropes Form the Basis of Protin-Resistanct Surfaces. Langmuir, 19, 2388-2391 (2003).

Synthesis of Free-Standing Quasis-Two_Dimentional Polymers, Langmuir, 19, 2466-2472 (2003).

“Microfluides” in Optical Biosensors : Present & Future, Eds Liglerand Rowe – Taitt, 571-595-(2002).

Study of the Basicity of the Amino Groups of the Aminologycoside Amikacin Using Capillary Electrophoresis.

Analytical Chemistry. 73, 4028 (2001)

Designing a Polyvalant Inhebitor of Antrax Toxin Nature Biotechnology, 19, 958 (2001)

Pattered Deposition of cellsand pritins onto surfaces by using Three – dimentional Microfluidic Systems. Proceedings of the national Academy of Sciences (USA), 97, 2408 (2008)

Patterning Mammalian Cells Using Elastomeric Membresnes, Langmuir, 16, 7811, (2000)

Multilayer nanoreactors for metallic and Semi-conducting Praticals. Langmuir, 16, 1354 (2000)

Pattering Protins and cells using Soft lithography, Biomaterials, 20, 2363 (1999)

डॉ. रवी शांताराम काणे यांना २०१० साली ठाणे येथे झालेल्या काणे संमेलनात काणे कुलप्रतिस्ठानचा ‘भारतरत्न, महामहोपाध्याय डॉ. पां. वा. काणे’ पुरस्कार देऊन त्यांच्या कार्याचा गौरव केला होता.